Saturday, May 23, 2020

Washington College Admissions and Acceptance Rate

Only around half of those who apply to Washington College are accepted. Learn more about the admissions requirements and what it takes to go to this college. About Washington College Founded in 1782 under the patronage of George Washington, Washington College has a long and rich history. The college was recently awarded a chapter of Phi Beta Kappa for its many strengths in the liberal arts and sciences. The Center for Environment Society, the C. V. Starr Center for the Study of the American Experience, and the Rose O’Neill Literary House are all valuable resources for supporting undergraduate education. Popular majors include Business Administration, Economics, English, Biology, and Psychology. Washington Colleges location in scenic Chestertown, Maryland, provides students with opportunities to explore the Chesapeake Bay watershed and the Chester River. On the athletic front, the Washington College Shoremen and Shorewomen compete in the NCAA Division III Centennial Conference. The college fields seven mens and nine womens varsity sports. Popular sports include basketball, soccer, swimming, tennis, and rowing. The college also has a co-ed sailing team. Admissions Data (2016) Washington College Acceptance Rate: 49  percentWashington College has test-optional admissionsGPA, SAT and ACT Graph for Washington CollegeWhat these SAT numbers meanTop Maryland colleges SAT comparisonWhat these ACT numbers meanTop Maryland colleges ACT comparison Enrollment (2016) Total Enrollment: 1,479  (all undergraduates)Gender Breakdown: 44 percent Male / 56 percent Female99  percent Full-time Costs (2016-17) Tuition and Fees: $43,842Books: $850 (why so much?)Room and Board: $10,824Other Expenses: $2,990Total Cost: $58,506 Washington College Financial Aid (2015-16) Percentage of New Students Receiving Aid: 98  percentPercentage of New Students Receiving Types of AidGrants: 98 percentLoans: 62 percentAverage Amount of AidGrants: $25,533Loans: $7,671 Academic Programs Most Popular Majors:  Biology, Business Administration, Economics, English, Environmental Studies, History, Political Science, Psychology, Environmental Studies Transfer, Graduation and Retention Rates First Year Student Retention (full-time students): 86  percent4-Year Graduation Rate: 70 percent6-Year Graduation Rate: 73  percent Intercollegiate Athletic Programs Mens Sports:  Lacrosse, Soccer, Rowing, Baseball, Basketball, Swimming, TennisWomens Sports:  Volleyball, Swimming, Soccer, Tennis, Softball, Rowing, Basketball, Lacrosse, Field Hockey Washington College and the Common Application Washington College uses the  Common Application. These articles can help guide you: Common Application essay tips and samplesShort answer tips and samplesSupplemental essay tips and samples If You Like Washington College, You May Also Like These Schools University of Delaware: Profile | GPA-SAT-ACT GraphTowson University: Profile | GPA-SAT-ACT GraphGoucher College: Profile | GPA-SAT-ACT GraphAmerican University: Profile | GPA-SAT-ACT GraphDrexel University: Profile | GPA-SAT-ACT GraphTemple University: Profile | GPA-SAT-ACT GraphHood College: Profile | GPA-SAT-ACT GraphBoston University: Profile | GPA-SAT-ACT GraphJohns Hopkins University: Profile | GPA-SAT-ACT GraphStevenson University: Profile  Georgetown University: Profile | GPA-SAT-ACT GraphUrsinus College: Profile | GPA-SAT-ACT Graph Washington College Mission Statement mission statement from http://www.washcoll.edu/about/our-mission.php Washington College challenges and inspires emerging citizen leaders to discover lives of purpose and passion. Data Source: National Center for Educational Statistics

Monday, May 11, 2020

How to Grow Salt Crystals

Table salt, also known as sodium chloride, is a crystal (a symmetrical solid substance made entirely of the same material).  You can see the shape of a salt crystal under a microscope, and you can grow your own salt crystals for fun or for a science fair. Growing salt crystals is fun and easy; the ingredients are right in your kitchen, the crystals are non-toxic, and no special equipment is required.   How to Grow Salt Crystals It takes very little work to start the process of growing salt crystals, though you will need to wait a few hours or days to see the results, depending on the method you use. No matter which method you try, youll need to use a hot stove and boiling water, so adult supervision is advised.   Salt Crystal Materials table salt (sodium chloride)waterclean clear containera piece of cardboard (optional)string and pencil or butter knife (optional) Procedures Stir salt into boiling hot water until no more salt will dissolve (crystals start to appear at the bottom of the container). Be sure the water is as close to boiling as possible. Hot tap water is not sufficient for making the solution. Quick Crystals:  If you want crystals quickly, you can soak a piece of cardboard in this supersaturated salt solution. Once it is soggy, place it on a plate or pan and set it in a warm and sunny location to dry out. Numerous small salt crystals will form. Perfect Crystals:  If you are trying to form a larger, perfect cubic crystal, you will want to make a seed crystal.  To grow a big crystal from a seed crystal, carefully pour the supersaturated salt solution into a clean container (so no undissolved salt gets in), allow the solution to cool, then hang the seed crystal in the solution from a pencil or knife placed across the top of the container. You could cover the container with a coffee filter if you like. Set the container in a location where it can remain undisturbed. You are more likely to get a perfect crystal instead of a mass of crystals if you allow the crystal to grow slowly (cooler temperature, shaded location) in a place free of vibrations. Tips for Success Experiment with different types of table salt. Try iodized salt, un-iodized salt, sea salt, or even salt substitutes. Try using different types of water, such as tap water compared with distilled water. See if there is any difference in the appearance of the crystals.If you are trying for the perfect crystal use un-iodized salt and distilled water. Impurities in either the salt or water can aid dislocation, where new crystals dont stack perfectly on top of previous crystals.The solubility of table salt (or any kind of salt) increases greatly with temperature. Youll get the quickest results if you start with a saturated saline solution, which means you want to dissolve salt in the hottest water available. One trick to increase the amount of salt you can dissolve is to microwave the salt solution. Stir in more salt until it stops dissolving and starts to accumulate at the bottom of the container. Use the clear liquid to grow your crystals. You can filter out the solids using a coffee f ilter or paper towel.

Wednesday, May 6, 2020

Ketamine Pain Mechanism Free Essays

Pain is communicated from the brain to other parts of the body by the CNS (Central Nervous System) and nerve endings. (Mayer, Mao, Holt, Price, 7731-7736) The ligand-gated ion channels, also referred to as LGICs, or ionotropic receptors, are a group of intrinsic transmembrane ion channels that are opened in response to binding of a chemical messenger. (Collingridge, Singer, 290-296) (Dickenson, 307-309) (Dickenson, Chapman, Green, 633-638) The ion channel is regulated by a neurotransmitter ligand that is very selective to one or more ions like potassium, sodium, calcium, and chloride. We will write a custom essay sample on Ketamine Pain Mechanism or any similar topic only for you Order Now (Kandel, Schwartz, Jessell, 178-180)   Such receptors located at synapses converting the chemical signal to an electric signal in the post-synaptic cell. (Connolly, Wafford, 529-534)   The NMDA receptor (N-methyl-D-aspartate) is such an ionotropic receptor for glutamate. (Dingledine, Borges, Bowie, Traynelis, 7-61) (Lodge, Johnson, 81-86) (Meller, 435-436)   By X-ray crystallography, the NMDA receptors have an heterodimer subunits, which are involved in the binding of agonists and antagonists like Ketamine. (Hirota, Lambert, 441-444) This channel complex contributes to excitatory synaptic transmission at sites throughout the brain and the spinal cord, and is modulated by a number of endogenous and exogenous compounds. (Rabben, Skljelbred, Oye, 1060-1066)   NMDA receptors play a key role in a wide range of physiologic and pathologic processes. (Hoffman, Coppejans, Vercauteren, Adriemsen, 240-242) (Klepstadt, Maurset, Moberg, Oye, 513-518) (Coderre, Katz, Vaccarino, Melzack, 259-285) Ketamine is primarily a non-competitive antagonist, which opens in response to binding of glutamate. This NMDA receptor mediates the reduction of pain effects of ketamine at low doses. (Lofwall, Griffiths, Mintzer, 439-449) Evidence for this is reinforced by the fact that naxolone, an opioid antagonist, does not reverse the analgesia. Studies also seem to indicate that ketamine is ‘use dependent’ meaning it only initiates its blocking action once a glutamate binds to the NMDA receptor. (Sorensen, Bengtsson, Ahlner, Henriksson, Ekselius et al., 1615-1621)   At high level doses, ketamine has also been found to bind to opioid mu receptors and sigma receptors. Thus, loss of consciousness that occurs may be partially due to binding at the opioid mu and sigma receptors. (Lonnqvist, Norton, 617-621) (Menigaux, Fletcher, Dupont, Guignard, Guirimand, et al. 129-135) (Koppert, Sittl, Scheuber, Alsheimer, Schmelz, 152-159) (Bushell, Endoh, Simen, Ren, Bindokas, 55-64) Works Cited Mayer DJ, Mao J, Holt J, Price DD. Cellular Mechanisms of Neuropathic Pain, Morphin Tolerance, and their Interactions. Proc. Natl Acac. Sci. USA. 1999, 96(14): 7731-7736. Collingridge G, Singer W. Excitatory Amino Acid Receptors and Synaptic Plasticity. Trends Pharmacol Sci. 1990 11: 290-296. Dickenson AH. A cure for wind-up: NMDA receptor antagonists as potential analgesics. Trends Pharmacol Sci 1990 11: 307-309 Dickenson AH, Chapman V and Green GM. The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen Pharmacol 1997 28: 633-638 Kandel ER, Schwartz JH, Jessell TM. Principles of Neural Science, 4th ed. McGraw-Hill: New York, (2000), pp.178-180 Connolly CN, Wafford KA. The Cys-Loop Superfamily of Ligand-Gated Ion Channels – the Impact of Receptor Structure on Function. Biochemical Society Transactions (2004) Vol. 32: 529-534. Dingledine R, Borges K, Bowie D, Taynelis SF. The Glutamate Receptors Ion Channels. Pharmacology Reviews, 1999 51(1): 7-61 Lodge D and Johnson KM. Non-Competitive Excitatory Amino Acid Antagonists. Trends Pharmacol Sci 1990 11: 81-86 Meller ST. Ketamine: Relief from Chronic Pain through Actions at the NMDA Receptor? Pain   1996 68: 435-436 Hirota K, Lambert DG. Ketamine: Its Mechanism (s) of Action and its Unusual Clinical Uses. Br. J. Anesth. 1996, 77(4):441-444. Rabben T, Skjelbred P, Oye I. Prolonged Analgesic Effects of Ketamine, an N-Methyl-D-Aspartate Receptor Inhibitor, in Patients with Chronic Pain. The Journal of Pharmacology and Experimental Pharmaceutics. 1999, 289(2):1060-1066. Hoffmann V, Coppejans H, Vercauteren M and Adriaemsen H Successful Treatment of Postherpetic Neuralgia with Oral Ketamine. 1994 Clin J Pain 10: 240-242 Klepstad P, Maurset A, Moberg ER and Oye I Evidence for a Role for NMDA Receptors in Pain Perception. Eur J Pharmacol   1990 187: 513-518 Coderre TJ, Katz J, Vaccarino AL and Melzack R.   Contribution of Central Neuroplasticity to Pathological Pain: A Review of Clinical and Experimental Evidence. 1993 Pain 52: 259-285. Lofwall MR, Griffiths RR, Mintzer MZ. Cognitive and Subjective Acute Dose Effects of Intramuscular Ketamine in Healthy Adults. Ex. Clin. Psychopharmacol. (2006), 14(4):439-449 Sorensen J, Bengtsson A, Ahlner J, Henriksson KG, Ekselius L and Bengtsson M.   Fibromyalgia. Are there different mechanisms in the processing of pain? A double Blind Crossover Comparison of analgesic Drugs. 1997 J Rheumatol 24: 1615-1621 Lonnqvist PA, Norton NS. Pediatric Day-Case Anesthesia and Pain Control.   Curr. Opin. Anaest. (2006), 19(6): 617-621. Menigaux C, Fletcher D, Dupont X, Guignard B, Guirimand F, Chauvin M. The Benefits of Intraoperative Small-Dose Ketamine on Postoperative Pain after Anterior Cruciate Ligament Repair. Anesth. Analg. 2000 90(1): 129-135 Koppert W, Sittl R, Scheuber K,Alsheimer M, Schmeltz M, Schuttler J. Differential Modulation of Remifentanil-Induced Analgesia and Post-Infusion Hyperalgesia by S-Ketamine and Clonidine in Humans. Anesthesiology. 2003, 99(1): 152-159. Bushell T, Endoh T, Simen AA, Ren D, Bindokas VP, Miller RJ. Molecular Components of Tolerance to Opiates In Single Hippocampal Neurons. Mol. Pharmacol. 2002, 61(1): 55-64. How to cite Ketamine Pain Mechanism, Essay examples